i.v. lidocaine demonstrates significant analgesic, anti-hyperalgesic, and anti-inflammatory properties. It also reduces sensitivity and activity of spinal cord neurones (central sensitization) and decreases N-methyl-d-aspartate receptor-mediated post-synaptic depolarization.This infusion helps to treat many conditions including Fibromyalgia, Chronic regional pain syndrome, neuropathic pain, chronic diabetic neuropathy and vascular headaches